| 名稱 | Recombinant Human IL-17 （IL-17A） |
| 型號 | |
| 更新時間 | 2022-09-24 |
| 特點 | 重組IL-17蛋白質,現在被稱為IL-17A,是136為兩個氨基酸鏈,激活t細胞,分泌的促炎和造血基質細胞誘導生產生物活性分子。重組人類IL-17A 31.3 kDa disulfide-linked為兩個137氨基酸的多肽鏈。使用所有無動物生產試劑。} |
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- 詳(xiang)細內容
一.產品名稱：Recombinant Human IL-17 (IL-17A)/Peprotech IL-17
二.Catalog Number:AF-200-17
三.Synonyms:IL-17, CTLA-8
四.Description:
The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant human IL-17A is a 31.3 kDa disulfide-linked homodimer of two 137 amino acid polypeptide chains. Manufactured using all non-animal reagents.
五.AA Sequence:
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
六.Source:E.coli
七(qi).Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
八.Biological Activity:Measured by its ability to induce IL-6 production by NHDF cells using a concentration range of 0.5-1.5 ng/ml.
九(jiu).Cross Reactivity:Human, Cow
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電話/傳真：13366128764
手機：15311648455
地址：北京市海淀區廂黃旗2號樓1層4-179室